The Ursinus Weekly, November 6, 1975

Lloyd joins German Dept. • Parking problems • AAUP speaker discusses Union • Student apprehended • Psych Club news • State of the Union • Hot flicks in Philly • Gurzynski hits century mark • Bearettes tie W. C. • Widener wallops whazoo\u27s woefuls! • Phila. Sixers\u27 hoopla • Here and there • El Espanol vivahttps://digitalcommons.ursinus.edu/weekly/1045/thumbnail.jp

The Ursinus Weekly, October 16, 1975

S.F.A.R.C. reps meet, discuss Library & proctors • Homecoming day is coming • Students, V.P. Richter discuss false alarm • Union plans mini-courses • Library Assoc. to meet at U.C. • New instructor • Editorial: Pride, not prejudice • Letter to the editor: Day vs. resident • Saturday Lunch • Speak up or give up • Freedom of speech • State of the Union • George Allen\u27s Ursinus Redskins • Our captains • Ursinus offense faltershttps://digitalcommons.ursinus.edu/weekly/1043/thumbnail.jp

The Ursinus Weekly, February 12, 1976

Students and Board meet • U.S.G.A. to be elected: Pres. qualifications amended • English Dept. upholds quality • ETS changes • Attorney named bequest chairman • Two Ursinus grads look back from Penn • Editorial: Schedule change - aid to program? • Civil Service testing set • Letter to the editor: A different opinion • Rich Swartz discusses his U.C. career • Movie review: One flew over the cuckoo\u27s nest • Shakespeare trip offered in June • Reflections on France • Forum review: Duo pianists • Lorelei news • Good: Badminton! • Our Bears do wrestle! • We have a winner! • NBA stars • How Vermeil got the Eagles job! • Bernie! • Intramurals! • Bears basketball • Notes from sports editor\u27s deskhttps://digitalcommons.ursinus.edu/weekly/1050/thumbnail.jp

The Ursinus Weekly, November 13, 1975

Volleyball team is Division A champ • Myrin hrs. changed? • Pre-legal Soc. is revived • SFARC update • U.S.A. as seen by Kahata • Temple University lists Irish Studies • Pollution expert talks • Editorial: Pride and perseverance • Editor\u27s comment: My reply to your opinions • Saturday Lunch • Forum review: Ambassador discusses U.N. • Bearpit opens • A new light on Lantern • Newmans organize • A conversation in the board room • Devils demonize Bears! • Diving into action • Intramurals • Mr. Karas • NBA West • A season of kickshttps://digitalcommons.ursinus.edu/weekly/1046/thumbnail.jp

The Ursinus Weekly, October 2, 1975

Meetings on Perkiomen Valley growth • In memoriam • Gene Shue presents: Year of the Sixers • City planner speaks • Ursinus College appoints Assoc. Prof. of Education • Kane earns Doctorate • Editorial: A different year? • Is there more to life? • New dorms renovated • Saturday Lunch • Forum series opens: Nina Deutsch • Musical notes • Chris Hillman rated • New events at Walnut • Nancy Drew revisited • Alumnus is named to Library post • British history specialist joins Ursinus faculty • Instructor returns to Ursinus • Pa. Dutch Program is success • Instructor appointed to Biology Dept. • Lindback Award presented • Soccer season opens • Ursinus allies with area • Balloons! • Ursinus named a \u2776er • Register now! • Grads elect officers • Yes we can gang didn\u27t • NFC forecast • MAC report • F & M stings Bears 35 - 21https://digitalcommons.ursinus.edu/weekly/1041/thumbnail.jp

Tackling gaps in developing life-changing treatments for dementia.

Since the G8 dementia summit in 2013, a number of initiatives have been established with the aim of facilitating the discovery of a disease-modifying treatment for dementia by 2025. This report is a summary of the findings and recommendations of a meeting titled "Tackling gaps in developing life-changing treatments for dementia", hosted by Alzheimer's Research UK in May 2018. The aim of the meeting was to identify, review, and highlight the areas in dementia research that are not currently being addressed by existing initiatives. It reflects the views of leading experts in the field of neurodegeneration research challenged with developing a strategic action plan to address these gaps and make recommendations on how to achieve the G8 dementia summit goals. The plan calls for significant advances in (1) translating newly identified genetic risk factors into a better understanding of the impacted biological processes; (2) enhanced understanding of selective neuronal resilience to inform novel drug targets; (3) facilitating robust and reproducible drug-target validation; (4) appropriate and evidence-based selection of appropriate subjects for proof-of-concept clinical trials; (5) improving approaches to assess drug-target engagement in humans; and (6) innovative approaches in conducting clinical trials if we are able to detect disease 10-15 years earlier than we currently do today

Measurement of W+W− production in association with one jet in proton–proton collisions at sqrt(s) = 8TeV with the ATLAS detector

The production of W boson pairs in association with one jet in pp collisions at View the MathML sources=8 TeV is studied using data corresponding to an integrated luminosity of 20.3 fb−1 collected by the ATLAS detector during 2012 at the CERN Large Hadron Collider. The cross section is measured in a fiducial phase-space region defined by the presence of exactly one electron and one muon, missing transverse momentum and exactly one jet with a transverse momentum above 25 GeV and a pseudorapidity of |η|<4.5|η|<4.5. The leptons are required to have opposite electric charge and to pass transverse momentum and pseudorapidity requirements. The fiducial cross section is found to be View the MathML sourceσWWfid,1-jet=136±6(stat)±14(syst)±3(lumi) fb. In combination with a previous measurement restricted to leptonic final states with no associated jets, the fiducial cross section of WW production with zero or one jet is measured to be View the MathML sourceσWWfid,≤1-jet=511±9(stat)±26(syst)±10(lumi) fb. The ratio of fiducial cross sections in final states with one and zero jets is determined to be 0.36±0.050.36±0.05. Finally, a total cross section extrapolated from the fiducial measurement of WW production with zero or one associated jet is reported. The measurements are compared to theoretical predictions and found in good agreement

Rehabilitation versus surgical reconstruction for non-acute anterior cruciate ligament injury (ACL SNNAP): a pragmatic randomised controlled trial

BackgroundAnterior cruciate ligament (ACL) rupture is a common debilitating injury that can cause instability of the knee. We aimed to investigate the best management strategy between reconstructive surgery and non-surgical treatment for patients with a non-acute ACL injury and persistent symptoms of instability.MethodsWe did a pragmatic, multicentre, superiority, randomised controlled trial in 29 secondary care National Health Service orthopaedic units in the UK. Patients with symptomatic knee problems (instability) consistent with an ACL injury were eligible. We excluded patients with meniscal pathology with characteristics that indicate immediate surgery. Patients were randomly assigned (1:1) by computer to either surgery (reconstruction) or rehabilitation (physiotherapy but with subsequent reconstruction permitted if instability persisted after treatment), stratified by site and baseline Knee Injury and Osteoarthritis Outcome Score—4 domain version (KOOS4). This management design represented normal practice. The primary outcome was KOOS4 at 18 months after randomisation. The principal analyses were intention-to-treat based, with KOOS4 results analysed using linear regression. This trial is registered with ISRCTN, ISRCTN10110685, and ClinicalTrials.gov, NCT02980367.FindingsBetween Feb 1, 2017, and April 12, 2020, we recruited 316 patients. 156 (49%) participants were randomly assigned to the surgical reconstruction group and 160 (51%) to the rehabilitation group. Mean KOOS4 at 18 months was 73·0 (SD 18·3) in the surgical group and 64·6 (21·6) in the rehabilitation group. The adjusted mean difference was 7·9 (95% CI 2·5–13·2; p=0·0053) in favour of surgical management. 65 (41%) of 160 patients allocated to rehabilitation underwent subsequent surgery according to protocol within 18 months. 43 (28%) of 156 patients allocated to surgery did not receive their allocated treatment. We found no differences between groups in the proportion of intervention-related complications.InterpretationSurgical reconstruction as a management strategy for patients with non-acute ACL injury with persistent symptoms of instability was clinically superior and more cost-effective in comparison with rehabilitation management